Fig. 9From: The discovery of regional neurotoxicity-associated metabolic alterations induced by carbon quantum dots in brain of mice using a spatial metabolomics analysisCQDs caused PD-like degeneration in mice. (a) Representative IHC staining images and quantitative results of TH positive cells in SNpc and TH positive terminals in striata; (b) Representative track and heatmap images in the open-field test, and the quantitative results of parameter analysis including total moved distance (c) and time spent in center (d); (e) The time to fall in suspension test; (f, g) The time to orient down and time to descend in pole-climbing test; (h) The scores of swim test. Data are showed as mean ± SD of three independent experiments. (*P < 0.05, **P < 0.01, ***P < 0.001)Back to article page