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Fig. 5 | Particle and Fibre Toxicology

Fig. 5

From: Titanium dioxide nanoparticles enhance thrombosis through triggering the phosphatidylserine exposure and procoagulant activation of red blood cells

Fig. 5

Thrombotic effects of TiO2 NPs exposure after intravenously injection to rat. (a) Blood was freshly collected from 8-week-old SD rats, and isolated rat RBCs were further incubated with various concentrations (0, 5, 10 and 25 μg/mL) of TiO2 NPs. (a, left) PS exposure as well as (a, right) thrombin generation were evaluated. (b) In a venous animal model, various doses of TiO2 NPs was intravenously injected to rats, and 1 h later, thrombus formation was assessed. Values are mean ± S.E. of 4–5 independent experiments, * represents significant differences from the control group (p < 0.05)

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Particle and Fibre Toxicology

ISSN: 1743-8977

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