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Fig. 4 | Particle and Fibre Toxicology

Fig. 4

From: Diesel exhaust particles alter the profile and function of the gut microbiota upon subchronic oral administration in mice

Fig. 4

Metabolic responses after oral DEP exposure Metabolic effects were measured in ApoE−/− (a, c, e, g, i) and C57Bl/6 (b, d, f, h, j) mice 3 and 6 months, respectively, after oral exposure to DEP. Glucose tolerance test (a, b; n = 4) and Insulin tolerance test (c, d; n = 6) responses were analyzed by a two-way ANOVA (dose*time interaction was not statistically significant). Plasma total cholesterol (e, f), HDL cholesterol (g, h) and triglycerides (TG) (i, j) were analyzed by a one-way ANOVA followed by a Dunnett’s test (** p ≤ 0.01) and a test for linear trend (indicated p values) (n = 8 for ApoE−/−, n = 10 for C57Bl/6)

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Particle and Fibre Toxicology

ISSN: 1743-8977

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