Table 2 Hematologic and blood chemical parameters of recovery group male rats exposed to benzalkonium chloride

Concentration (mg/m³)

0

0.8

4

20

0

0.8

4

20

 WBC (×10³/μL)

4.65 ± 1.10

4.65 ± 0.50

4.48 ± 0.92

4.64 ± 0.71

4.70 ± 0.46

5.38 ± 0.69

4.45 ± 0.54

3.74 ± 1.15

 RBC (×10⁶/μL)

9.02 ± 0.31

8.98 ± 0.112

8.96 ± 0.27

8.95 ± 0.16

8.89 ± 0.10

9.00 ± 0.19

8.89 ± 0.16

8.77 ± 0.31

 HCT (%)

43.68 ± 1.37

43.40 ± 0.68

43.66 ± 0.84

44.22 ± 0.93

42.16 ± 0.26

42.62 ± 0.66

42.52 ± 0.44

42.78 ± 1.71

 Hb (g/dL)

14.84 ± 0.47

14.72 ± 0.30

14.72 ± 0.34

14.90 ± 0.29

14.28 ± 0.24

14.46 ± 0.22

14.38 ± 0.15

14.38 ± 0.50

 MCV (fL)

48.42 ± 0.36

48.32 ± 0.36

48.80 ± 0.68

49.38 ± 0.21^b

47.40 ± 0.39

47.32 ± 0.40

47.84 ± 0.54

48.74 ± 0.55^b

 MCH (g/dL)

16.4 ± 0.1

16.4 ± 0.2

16.4 ± 0.2

16.7 ± 0.1

16.00 ± 0.09

16.10 ± 0.11

16.10 ± 0.25

16.40 ± 0.07^b

 MCHC (g/dL)

33.91 ± 0.07

33.94 ± 0.25

33.70 ± 0.30

33.74 ± 0.30

33.92 ± 0.43

33.96 ± 0.13

33.78 ± 0.31

33.60 ± 0.27

 RETA (×10⁹/L)

250.48 ± 34.86

256.74 ± 5.45

328.56 ± 47.76^b

319.96 ± 30.79^a

270.34 ± 16.42

239.50 ± 18.57

280.40 ± 25.11

292.90 ± 20.89

 RET (%)

2.78 ± 0.40

2.86 ± 0.05

3.67 ± 0.58^b

3.58 ± 0.33^a

3.04 ± 0.18

2.66 ± 0.25

3.15 ± 0.32

3.34 ± 0.18

 PLT (×10³/μL)

788.0 ± 37.29

816.4 ± 11.78

871.4 ± 32.55^c

872.2 ± 21.35^c

787 ± 20

773 ± 43

806 ± 36

789 ± 49

 LYMA (×10³/μL)

3.23 ± 0.87

3.37 ± 0.37

3.13 ± 0.84

3.29 ± 0.42

3.40 ± 0.44

3.89 ± 0.27

2.89 ± 0.72

2.58 ± 0.87

 MONA (×10³/μL)

0.12 ± 0.05

0.10 ± 0.37

0.11 ± 0.03

0.13 ± 0.05

0.11 ± 0.03

0.12 ± 0.02

0.12 ± 0.02

0.08 ± 0.01

 EOSA (×10³/μL)

0.07 ± 0.01

0.07 ± 0.01

0.06 ± 0.01

0.07 ± 0.02

0.07 ± 0.03

0.08 ± 0.02

0.06 ± 0.02

0.06 ± 0.01

 EOS% (%)

1.44 ± 0.21

1.52 ± 0.26

1.28 ± 0.30

1.48 ± 0.16

1.48 ± 0.48

1.48 ± 0.31

1.42 ± 0.43

1.68 ± 0.31

 APTT (sec)

19.48 ± 2.32

18.92 ± 0.66

19.12 ± 0.35

21.04 ± 3.60

16.54 ± 0.68

17.22 ± 0.42

16.70 ± 0.44

16.90 ± 0.57

 APT (sec)

10.28 ± 0.16

10.72 ± 0.52

9.98 ± 0.11

10.24 ± 0.24

10.46 ± 0.35

10.68 ± 0.26

10.38 ± 0.42

11.42 ± 0.46^b

 ALT (IU/L)

49.40 ± 23.18

39.28 ± 2.88

40.52 ± 1.10

42.12 ± 2.80

41.40 ± 1.05

43.18 ± 1.00

42.18 ± 1.25

45.02 ± 6.36

 ALP (IU/L)

695.52 ± 28.52

688.96 ± 29.80

777.70 ± 51.71^a

770.64 ± 54.58^a

594.10 ± 24.24

579.14 ± 23.36

648.06 ± 40.10

680.92 ± 62.32^a

 TG (mg/dL)

74.30 ± 9.57

66.82 ± 12.77

74.64 ± 24.61

63.28 ± 9.17

104.52 ± 25.24

84.08 ± 27.14

94.68 ± 37.22

59.40 ± 18.83

 CK (U/L)

311.82 ± 119.04

270.86 ± 127.51

298.22 ± 125.41

290.66 ± 107.74

453.02 ± 114.84

400.54 ± 191.10

384.44 ± 151.55

435.16 ± 225.82

 Cl (mmol/L)

102.48 ± 1.21

103.94 ± 0.85

104.10 ± 0.88

103.24 ± 1.44

102.24 ± 1.30

103.20 ± 1.39

103.96 ± 0.40

104.20 ± 0.91^a

 K (mmol/L)

4.56 ± 0.68

4.36 ± 0.53

4.34 ± 0.57

4.92 ± 1.06

4.40 ± 0.46

4.52 ± 0.80

5.04 ± 0.42

4.56 ± 0.80

 Na (mmol/L)

143.74 ± 1.44

144.24 ± 0.81

144.92 ± 0.41

143.92 ± 1.43

143.40 ± 0.68

143.50 ± 0.62

144.34 ± 0.44^a

144.64 ± 0.49^b