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Fig. 15 | Particle and Fibre Toxicology

Fig. 15

From: Exposure to diesel exhaust particles results in altered lung microbial profiles, associated with increased reactive oxygen species/reactive nitrogen species and inflammation, in C57Bl/6 wildtype mice on a high-fat diet

Fig. 15

Probiotic supplementation decreases collagen deposition surrounding the bronchioles. a Representative images of lung tissue sections stained with Masson’s trichrome in of 4–6 week-old C57Bl/6 wildtype mice on high-fat (HF) diet exposed to either saline (control) or diesel exhaust particles (DEP – 35 μg PM) twice a week for a total of 30 days alongside a dose of 0.3 g/day (~ 7.5 × 107 cfu/day) of Ecologic® Barrier probiotics in the drinking water over the course of the exposures. Blue areas indicate collagen deposition. b Graph of histology scoring of Masson’s trichrome staining. 20x magnification, scale bar = 240 μm. Data are depicted as mean ± SEM with ‡p < 0.05 compared to HF DEP by two way ANOVA

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Particle and Fibre Toxicology

ISSN: 1743-8977

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