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Fig. 6 | Particle and Fibre Toxicology

Fig. 6

From: Inhaled gold nanoparticles cause cerebral edema and upregulate endothelial aquaporin 1 expression, involving caveolin 1 dependent repression of extracellular regulated protein kinase activity

Fig. 6

Inhaled Au-NPs upregulated AQP1 expression in cerebral microvessels in vivo. a Representative images showed an increase in immunoreactivity against AQP1 in microvessels of brain tissues, whereas the stained CD31 (an endothelial biomarker) was without significant differences. b The quantitative data was determined by the measurement of the length of AQP1-positive microvessels. (** p < 0.01, and *** p < 0.001 indicates statistically significant difference from the control group, N = 4)

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