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Table 2 Correlation between mortality recorded at day 18 and Ni/Co content or Ni/Co released by the particles

From: HIF-1α is a key mediator of the lung inflammatory potential of lithium-ion battery particles

 

Correlation coefficient

p-value

Co content

−0.064

0.801

Ni content

0.760

0.0002

Bioaccessible Co

−0.079

0.755

Bioaccessible Ni

0.719

0.001

Ni + Co content

0.163

0.517

Bioaccessible Ni + Co

0.176

0.484

  1. Mice were treated with 0.5, 1 or 2 mg LIB particles (see Fig. 2). Bivariate analysis (Spearman Rho) between the mortality % at day 18, and the particle Ni and/or Co content (μg) or the amount of Ni and/or Co ions (μg) released. Co and/or Ni contents were calculated from the administered doses and from the Co and/or Ni % of the particles. Bioaccessible Co and/or Ni represent the amount of bioaccessible ions, calculated from the Co/Ni contained in the administered doses and the % released at pH 4.2 at day 14 (mortality was recorded between day 6 and 18). Significant relationships are identified in bold