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Fig. 3 | Particle and Fibre Toxicology

Fig. 3

From: In utero exposure to ultrafine particles promotes placental stress-induced programming of renin-angiotensin system-related elements in the offspring results in altered blood pressure in adult mice

Fig. 3

In utero exposure to UFP induces placental dysfunction and promotes activation of hypothalamic pituitary adrenal axis (HPA). a Protein levels and representative image of Western blot of placenta HSD11B2. n = 6/group; * p < 0.05. One-way ANOVA. b DNA methylation of the HSD11B2 promoter in placenta determined by pyrosequencing. n = 4/group; * p < 0.05. Two-way ANOVA. c Dam serum cortisol and d fetus cortisol were determined by ELISA. n = 4/group. Data are expressed as mean ± SEM. *p < 0.05 and ** p < 0.01. One-way ANOVA

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Particle and Fibre Toxicology

ISSN: 1743-8977

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