Particle and Fibre Toxicology

Table 1 In vivo OF Exposure of PAHs

From: Differential effects of diesel exhaust particles on T cell differentiation and autoimmune disease

PAHs	ng PAH per in vivo OF exposure			ng PAH per in vivo OF exposure
PAHs	SRM1650b	8 h	24 h	SRM2975	8 h	24 h
Phenanthrene	218.86	21,886	7295.22	50.583	5058.3	1686.1
Anthracene	13.790	1379.0	459.67	0	0	0
Fluoranthene	231.36	23,136	7711.89	115.13	11,513	3837.5
Pyrene	212.25	21,225	7075.05	0	0	0
Benz[a]anthracene	49.024	4902.4	1634.13	0	0	0
Chrysene	193.61	19,361	6453.59	29.519	2951.9	983.97
Benzo[b]fluoranthene	38.278	3827.8	1275.92	38.830	3883.0	1294.3
Benzo[k]fluoranthene	23.077	2307.7	769.23	0	0	0
Benzo[e]pyrene	30.440	3044.0	1014.65	3.2600	326.00	108.67
Benzo[a]pyrene	6.3570	635.70	211.90	0	0	0
Perylene	0	0	0	0	0	0
Indeno[1,2,3-cd]pyrene	27.830	2783.0	927.65	4.9558	495.58	165.19
Benzo[g,h,i]perylene	31.017	3101.7	1033.9	0	0	0
Dibenz[a,h]anthracene	0	0	0	0	0	0
Picene	0	0	0	0	0	0
Sum of PAHs	1075.9 ng	107,590 ng/m³	35,863 ng/m³	242.27 ng	24,227 ng/m³	8075.8 ng/m³

The nanograms of each PAH in the 20 μL OF exposure were calculated based on a dose of 12.5 mg/mL SRM1650b OF or SRM2975 OF. The 8 h and 24 h air exposure equivalents were calculated based on the nanograms of PAHs per exposure and the amount of air a mouse would breathe in 8 h, which is 0.01m³, and 24 h, which is 0.03m³

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