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Table 2 LOAELs (μg/cm2) for cytotoxicity and oxidative stress effects determined after 24 h of exposure

From: Predicting the in vivo pulmonary toxicity induced by acute exposure to poorly soluble nanomaterials by using advanced in vitro methods

  1. aLOAELs indicated represent significant cytotoxicity > 5%
  2. Significant effects allowing the determination of a LOAEL
  3. No significant adverse effects observed
  4. bDoses tested at the ALI: 0.1, 1, 3 μg/cm2
  5. cDoses tested in submerged conditions in inserts: 1, 3, 10 μg/cm2
  6. dDoses tested in submerged conditions in plates: 1, 3, 10, 20 μg/cm2
  7. eDoses tested in vivo: 0.001, 0.01, 0.1 μg/cm2