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Fig. 7 | Particle and Fibre Toxicology

Fig. 7

From: Early-life exposure to three size-fractionated ultrafine and fine atmospheric particulates in Beijing exacerbates asthma development in mature mice

Fig. 7

The mRNA expression levels of Th2 cytokines and chemokines in mouse lungs were measured by real-time PCR. a The regulation of Th2 type cytokines and IL-33 was observed in an asthma model with mice previously exposed to PM as infants. b mRNA expression of eosinophil-attracting chemokine Ccl11, and Th2 chemokines was more strongly triggered in mouse lungs following PM exposure as infants. Data are expressed as means ± SEM (n = 5 mice/group). *p < 0.05 vs. Con group; #p < 0.05 vs. OVA group, &p < 0.05 vs. OVA/PM (F1, F2 or F3)

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