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Fig. 4 | Particle and Fibre Toxicology

Fig. 4

From: Early-life exposure to three size-fractionated ultrafine and fine atmospheric particulates in Beijing exacerbates asthma development in mature mice

Fig. 4

Effects of PM exposure on DNMTs in vitro and in vivo. a and b The effect of PM treatment on mRNA expression of DNMTs in vitro. RAW 264.7 cells were exposed to 25 μg/ml PM for 5 h. c and d mRNA expression of DNMTs in lung tissues of mice was assessed 48 h following exposure to PM three times on the 17th, 19th and 21st days of postnatal age. n = 5 mice/group. Data are expressed as mean ± SEM. *p < 0.05 vs. Con group, &p < 0.05 vs. OVA/PM (F1, F2 or F3)

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