Fig. 3
Effects of NAC administration on cPMD-induced damage. All mice inhaled PM. Mice that received NAC (15 μg/kg/day for 14 days) in drinking water were compared with CT mice that did not receive NAC in drinking water. a Serum MDA concentration. b BALF cellularity. c iNKT cell count in the lung measured by flow cytometry. d qPCR analysis of cytokine and chemokine mRNA levels in the lung. e qPCR analysis of mRNA levels of oxidative stress markers in the lung. f Colon MPO activity. g qPCR analysis of cytokine and chemokine mRNA levels in the colon. Data are presented as mean ± SEM. *p < 0.05, **p < 0.01, ***p < 0.001, Mann–Whitney U test