Fig. 2
From: Silica nanoparticles inhibit the cation channel TRPV4 in airway epithelial cells
TRPV4 does not mediate the increase in basal [Ca2+]i induced by SiNPs in 16HBE cells. a Lack of correlation of the amplitudes of the intracellular Ca2+ responses to 300 μg/ml SiNPs and to the TRPV4 agonist GSK047067 (10 nM). b Effect of 300 μg/ml SiNPs in the absence (Control) and in the presence of the TRPV4 inhibitor HC067047 (10 μM). The lines represent average responses of 120 and 164 cells in control and HC067047, respectively