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Fig. 9 | Particle and Fibre Toxicology

Fig. 9

From: Comparison between micro- and nanosized copper oxide and water soluble copper chloride: interrelationship between intracellular copper concentrations, oxidative stress and DNA damage response in human lung cells

Fig. 9

Impact of CuO NP, CuO MP and CuCl2 on cell cycle distribution. BEAS-2B cells were treated with the different copper compounds for 8 h. Shown are mean values of four determinations derived from two independent experiments + SD. Statistically significant different from control: *p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001 (ANOVA-Dunnett’s T test). The numbers right to each bar indicate the fraction of cells in the respective phase. Please note the different concentrations used for the respective copper compound. 20 μg/mL CuO are equal to 252 μM Cu2+

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