Skip to main content
Fig. 6 | Particle and Fibre Toxicology

Fig. 6

From: Interaction of rat alveolar macrophages with dental composite dust

Fig. 6

Cytolysis of L-929 cells after exposure to supernatans of NR8383 macrophages exposed to the respirable fraction of composite dust, indicating the release of TNF-α. Data are presented as mean and standard error of the mean. The concentration of filtered composite dust (X-axis) is expressed in μg/ml. The numbers above the bars indicate statistically significant difference compared to the control (1: p < 0.05; 2: p < 0.01 and 3: p < 0.001). The black dotted line in each diagram indicates the level of non-treated cell controls. L-929 fibroblasts subjected to N8383 macrophage supernatant underwent apoptosis at high concentrations (180 μg/ml) of GrandiO, Z100MP Filtek Supreme and Tetric EvoCeram, indicating release of bioactive TNF-α

Back to article page