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Table 4 Dose deposited in submerged conditions in function of nominal concentration in suspensions

From: Air-liquid interface exposure to aerosols of poorly soluble nanomaterials induces different biological activation levels compared to exposure to suspensions

  

24 h deposition in plates

3 h deposition in inserts

TiO2 NM105

Nominal dose (μg/mL)

10

50

100

200

54.5

163.5

544.9

Nominal dose (μg/cm2)

2.5

12.5

25

50

11.7

35.0

116.7

Estimated dose using the ISDD model (μg/cm2)

0.7

3.6

7.1

14.3

1

3

10

TiO2 NM101

Nominal dose (μg/mL)

4

10

50

100

23.4

70.1

233.5

Nominal dose (μg/cm2)

1

2.5

12.5

25

5.0

15.0

50.0

Estimated dose using the ISDD model (μg/cm2)

1.0

2.5

12.5

25.0

1

3

10

TiO2 NM100

Nominal dose (μg/mL)

4

10

50

100

34.3

102.9

343.1

Nominal dose (μg/cm2)

1

2.5

12.5

25

7.3

22.0

73.5

Estimated dose using the ISDD model (μg/cm2)

0.7

1.8

8.8

17.5

1

3

10

CeO2 NM212

Nominal dose (μg/mL)

10

50

100

200

42.5

127.4

424.5

Nominal dose (μg/cm2)

2.5

12.5

25

50

9.1

27.3

90.9

Estimated dose using the ISDD model (μg/cm2)

0.9

4.7

9.5

18.9

1

3

10

Tested doses about (μg/cm2)

1

3

10

20

1

3

10