Items | Cu NPs (mg/kg/day) | |||
0 | 100 | 200 | 400 | |
No. of rats | 10 | 10 | 10 | 10 |
RBC (1012/L) | 7.02 ± 0.234a | 6.69 ± 0.388 | 6.17 ± 0.346** | 6.12 ± 0.612** |
HB (g/dL) | 16.78 ± 1.212 | 15.77 ± 1.668 | 12.70 ± 1.628** | 11.80 ± 1.187** |
HCT (%) | 43.43 ± 3.435 | 42.50 ± 2.432 | 37.32 ± 3.179** | 36.47 ± 5.747** |
MCV (fl) | 53.73 ± 4.388 | 50.09 ± 4.618 | 43.63 ± 9.582** | 43.60 ± 4.486** |
MCH (pg) | 23.47 ± 1.598 | 21.31 ± 2.788 | 19.10 ± 3.306** | 18.92 ± 2.099** |
MCHC (g/dL) | 34.68 ± 2.770 | 34.57 ± 3.317 | 33.05 ± 4.339 | 28.31 ± 2.198** |
PLT (109/L) | 1106.2 ± 104.92 | 1212.7 ± 125.88 | 1258.8 ± 166.73* | 1262.4 ± 121.65* |
RET (%) | 2.3 ± 0.23 | 2.4 ± 0.51 | 2.7 ± 0.48 | 6.1 ± 2.17** |
WBC (109/L) | 11.2 ± 0.95 | 11.3 ± 2.13 | 8.5 ± 3.03* | 8.3 ± 1.21** |
NEU (%) | 11.9 ± 0.95 | 11.2 ± 3.45 | 23.9 ± 5.41** | 36.6 ± 8.15** |
LYM (%) | 82.3 ± 10.73 | 82.3 ± 12.79 | 71.7 ± 13.28 | 52.7 ± 20.17** |
MON (%) | 2.2 ± 0.39 | 2.2 ± 0.33 | 2.3 ± 0.51 | 3.0 ± 0.59** |
EOS (%) | 1.7 ± 0.39 | 1.7 ± 0.33 | 1.6 ± 0.53 | 2.0 ± 0.59 |
BAS (%) | 0.7 ± 0.21 | 0.8 ± 0.18 | 0.7 ± 0.27 | 0.7 ± 0.19 |
LUC (%) | 0.7 ± 0.13 | 0.7 ± 0.24 | 1.0 ± 0.19* | 1.2 ± 0.25** |
Items | Cu MPs (mg/kg/day) | |||
 | 0 | 100 | 200 | 400 |
No. of rats | 10 | 10 | 10 | 10 |
RBC (1012/L) | 7.04 ± 0.312 | 7.20 ± 0.286 | 7.00 ± 0.403 | 6.96 ± 0.388 |
HB (g/dL) | 16.65 ± 1.326 | 16.72 ± 1.169 | 15.96 ± 1.563 | 16.12 ± 1.971 |
HCT (%) | 43.79 ± 4.793 | 43.61 ± 4.201 | 40.16 ± 5.776 | 41.63 ± 3.304 |
MCV (fl) | 53.81 ± 5.716 | 52.70 ± 6.621 | 52.63 ± 4.184 | 52.34 ± 7.206 |
MCH (pg) | 23.61 ± 3.392 | 24.32 ± 2.562 | 24.52 ± 1.397 | 22.93 ± 4.257 |
MCHC (g/dL) | 34.71 ± 3.392 | 29.67 ± 5.561 | 32.09 ± 3.397 | 32.25 ± 4.257 |
PLT (109/L) | 1179.7 ± 202.53 | 1047.4 ± 218.36 | 1259.8 ± 187.54 | 1236.5 ± 232.71 |
RET (%) | 2.5 ± 0.58 | 2.6 ± 0.37 | 2.4 ± 0.39 | 2.7 ± 0.44 |
WBC (109/L) | 11.3 ± 1.49 | 11.9 ± 2.48 | 12.3 ± 3.49 | 11.56 ± 2.23 |
NEU (%) | 12.2 ± 2.23 | 10.8 ± 3.91 | 13.2 ± 4.45 | 11.9 ± 3.71 |
LYM (%) | 82.9 ± 13.2 | 85.0 ± 22.47 | 82.7 ± 16.66 | 83.5 ± 13.09 |
MON (%) | 2.2 ± 0.48 | 2.3 ± 0.31 | 2.5 ± 0.43 | 2.3 ± 0.54 |
EOS (%) | 1.6 ± 0.42 | 1.5 ± 0.24 | 1.6 ± 0.40 | 1.8 ± 0.48 |
BAS (%) | 0.7 ± 0.23 | 0.7 ± 0.17 | 0.8 ± 0.13 | 0.7 ± 0.21 |
LUC (%) | 0.7 ± 0.22 | 0.9 ± 0.29 | 0.9 ± 0.29 | 0.9 ± 0.23 |