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Table 2 Biochemical tests including BUN, creatinine, GOT and GPT after i.p. injection of ZnO NPs

From: The role of hypoxia-inducible factor-1α in zinc oxide nanoparticle-induced nephrotoxicity in vitro and in vivo

Item/Group

0 mg/kg

1 mg/kg

2 mg/kg

4 mg/kg

BUN (mg/dL)

18.76 ± 3.75

23.46 ± 3.06

19.38 ± 0.57

23.40 ± 1.67*

Creatinine (mg/dL)

0.26 ± 0.02

0.33 ± 0.02*

0.33 ± 0.03*

0.35 ± 0.04*

GOT (U/L)

114.20 ± 22.13

116.40 ± 17.77

153.20 ± 27.40*

168.60 ± 29.53*

GPT (U/L)

31.80 ± 0.84

32.00 ± 3.32

34.40 ± 2.88

36.40 ± 1.52*

  1. *p < 0.05, ZnO NPs versus control