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Table 4 Cerium concentration in different tissues at 2 hours after intravenous injection of uncoated or silica-coated CeO2 NPs

From: Erratum to: Silica coating influences the corona and biokinetics of cerium oxide nanoparticles

 

CeO2

Silica-coated CeO2

 

ng/g ± SE

ng/g ± SE

Lungs

143.7 ± 17.9

546.2 ± 49.3*

Liver

19517.9 ± 444.9

16636.8 ± 676.7*

Bone

33.8 ± 4.4

64.2 ± 11.4*

Cecum

6.2 ± 4.3

2.1 ± 0.3

Large intestine

3.6 ± 0.9

2.8 ± 0.5

Bone marrow

17.3 ± 3.4

467 ± 7.0*

Spleen

16807.1 ± 3579.1

12043.8 ± 1717.6

Stomach

37.7 ± 16.7

47.7 ± 23.8

Kidneys

30.9 ± 14.4

52.7 ± 2.9

Small intestine

13.7 ± 2.0

11.2 ± 1.4

Heart

7.7 ± 1.5

14.1 ± 2.6

Testes

0.9 ± 0.2

1.9 ± 0.1*

Skeletal muscle

1.6 ± 0.5

2.3 ± 0.1

Brain

0.4 ± 0.0

1.1 ± 0.2*

Skin

2.0 ± 0.3

6.8 ± 0.4*

Plasma

1.4 ± 0.3

1.4 ± 0.3

RBC

26.6 ± 5.1

20.7 ± 2.3

  1. Data are mean ± SE ng/g cerium concentration, n = 5/group
  2. Ce concentration was estimated (ng/μCiNPs x μCi/gtissue)
  3. *P < 0.05, CeO2 vs. silica-coated CeO2