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Fig. 7 | Particle and Fibre Toxicology

Fig. 7

From: Multi-walled carbon nanotubes directly induce epithelial-mesenchymal transition in human bronchial epithelial cells via the TGF-β-mediated Akt/GSK-3β/SNAIL-1 signalling pathway

Fig. 7

TGF-β production (a) and lung hydroxyproline content (b) in C57BL/6 mice exposed to MWCNT. a C57BL/6 mice were exposed to sterile water (control, CTRL, black circle) or 120 μg of pMWCNT (white square) or MWCNTg (black square) for 15, 30 and 60 days. At the end BAL were collected and used for TGF-β measurement by ELISA. Versus control *p < 0.0001; Versus control °p < 0.0001. b Content of hydroxyproline measured in lung tissue of animals exposed to pMWCNT (white bars) and MWCNTg (black bars) compared to controls (CTRL, grey bars). Versus control *p < 0.05; Versus control °p < 0.05

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