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Fig. 4 | Particle and Fibre Toxicology

Fig. 4

From: Multi-walled carbon nanotubes directly induce epithelial-mesenchymal transition in human bronchial epithelial cells via the TGF-β-mediated Akt/GSK-3β/SNAIL-1 signalling pathway

Fig. 4

Akt/GSK-3β/SNAIL-1 signalling pathway in BEAS-2B cells exposed to MWCNTg. Cells were incubated in either the absence (0 μg/ml, control) or presence of 44 μg/ml of MWCNTg from 30 min to 8 h (a), together with the specific GSK-3β inhibitor SB216763 (b), GSK-3β siRNA (c), the specific Akt 1/2 Kinase Inhibitor (d) or Akt 1/2 siRNA (e). Each figure is representative of three experiments giving similar results

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