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Fig. 6 | Particle and Fibre Toxicology

Fig. 6

From: Intravenous administration of silver nanoparticles causes organ toxicity through intracellular ROS-related loss of inter-endothelial junction

Fig. 6

The viability and intracellular ROS of cells exposed with AgNPs or AgNO3. a Cell viability from CCK-8 assay. b The intracellular ROS level caused by AgNPs or AgNO3 exposure for 1 h. The H2O2 group was set as positive control. The * represents significant difference between control group and AgNP-75 treated group (*: p < 0.05, **: p < 0.01). c Representative fluorescence images of cells stained by DCFH-DA, in which (a) control group, (b and c) cells incubated with AgNO3 at 1 μg/mL and 10 μg/mL of Ag, (d) cells exposed to 7.5 mg/mL H2O2, (e-h) cells treated with 1, 10, 20 and 40 μg/mL AgNP-75. The scale bar represents 50 μm

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