Morphometric analysis of inflammation in bronchial biopsies following exposure to inhaled diesel exhaust and allergen challenge in atopic subjects

Table 3 Percent positivity for inflammatory biomarkers’ expression in the lung submucosa. Data are expressed as mean ± standard error of the mean (SEM)

Exposure condition	AA1	ECP	NE	CD138	CD4	IL-4
FAS	0.460 ± 0.053	0.308 ± 0.102	0.045 ± 0.014	0.017 ± 0.006	0.045 ± 0.014	0.127 ± 0.062
DES	0.681 ± 0.153	0.471 ± 0.175	0.077 ± 0.024	0.044 ± 0.024	0.045 ± 0.014	0.353 ± 0.088
FAA	0.646 ± 0.128	0.553 ± 0.109	0.229 ± 0.069	0.044 ± 0.008*	0.045 ± 0.014	0.426 ± 0.130
DEA	0.738 ± 0.159	0.487 ± 0.201	0.224 ± 0.047*	0.120 ± 0.031^, ^, **	0.045 ± 0.014*	0.548 ± 0.143*

FAS filtered air + saline, DES DE + saline, FAA filtered air + allergen, DEA DE + allergen, AA1 tryptase, ECP eosinophil cationic protein, NE neutrophil elastase
*p < 0.05, compared with FAS; **p < 0.05, compared with DES; ***p < 0.05, compared with DEA

ISSN: 1743-8977