Table 3 Concentrations of half-maximal basophil activation (C50) of free allergen versus AuNP-allergen conjugates for all donors tested. In conjugates the given values refer to the amounts of coupled allergen. Donors displaying X were tested but could not be statistically evaluated
| Â | C50 [ng/ml] | |||||
|---|---|---|---|---|---|---|
Donor | Bet v 1 | AuNP-Bet v 1 conjugates | Der p 1 | AuNP-Der p 1 conjugates | Phl p 5 | AuNP-Phl p 5 conjugates |
1 | X | X | X | X | X | X |
2 | 178 | 1 | 4 | 2 | X | X |
3 | 444 | 51 | 186 | 55 | X | X |
4 | 52 | 13 | 27 | 1 | 16 | 19 |
5 | 287 | 548 | 58 | 20 | X | X |
6 | 78 | 107 | --- | --- | 1 | 1 |
7 | 48 | 43 | --- | --- | 29 | 12 |
8 | 2 | 2 | --- | --- | 65 | 77 |
9 | 12 | 89 | --- | --- | --- | --- |