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Table 2 Cerium concentration at 28 days post-instillation of uncoated or silica-coated CeO2 NPs

From: Silica coating influences the corona and biokinetics of cerium oxide nanoparticles

 

CeO2

Silica-coated CeO2

 

ng/g ± SE

ng/g ± SE

Lungs

136836.67 ± 4084.19

95193.25 ± 1766.39 *

Liver

59.35 ± 10.19

33.10 ± 2.78 *

Bone

38.13 ± 5.14

21.97 ± 2.87 *

Cecum

33.62 ± 10.95

24.15 ± 6.58

Large intestine

28.11 ± 8.94

24.33 ± 8.01

Bone marrow

16.55 ± 2.55

9.44 ± 1.05 *

Spleen

13.90 ± 6.21

3.83 ± 0.59

Stomach

12.77 ± 2.09

16.82 ± 8.64

Kidneys

10.40 ± 1.13

5.52 ± 0.35 *

Small intestine

10.14 ± 1.49

7.94 ± 2.20

Heart

1.95 ± 0.54

0.21 ± 0.08 *

Testes

0.54 ± 0.08

0.13 ± 0.04 *

Skeletal muscle

0.46 ± 0.21

0.20 ± 0.09

Brain

0.43 ± 0.24

0.15 ± 0.11

Skin

0.38 ± 0.08

0.16 ± 0.01 *

Plasma

0.14 ± 0.09

0.04 ± 0.04

RBC

0.04 ± 0.04

0.08 ± 0.06

  1. Data are mean ± SE ng/g cerium concentration, n = 5/group
  2. Ce concentration was estimated (ng/μCiNPs x μCi/gtissue)
  3. *P < 0.05, CeO2 vs. silica-coated CeO2
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Particle and Fibre Toxicology

ISSN: 1743-8977

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