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Fig. 7 | Particle and Fibre Toxicology

Fig. 7

From: Effects of prenatal inhalation exposure to copper nanoparticles on murine dams and offspring

Fig. 7

Lung histopathology. Lung from mice exposed to Cu NPs and euthanized immediately after C-section on GD 19 (0 PND) exhibited histopathologic changes including mild to moderate, multifocal inflammatory cell infiltration within the interstitium which is composed primarily of lymphocytes and neutrophils with fewer plasma cells and macrophages (thick arrows). Also present was multifocal accumulations of a basophilic, flocculent, amorphous material (thin arrows). The pathology findings were more pronounced in non-pregnant mice as opposed to the pregnant group. There were no pathologic findings in control mice. Bars = 200 μm (inset, bars = 20 μm)

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