Lung inflammation and lack of genotoxicity in the comet and micronucleus assays of industrial multiwalled carbon nanotubes Graphistrength© C100 after a 90-day nose-only inhalation exposure of rats

Table 5 Biochemistry parameters in the BALF of male and female rats 24 h and 90 days after a 90-day exposure to Graphistrength^© C100

Concentration (mg/m³)	Phospholipids mmol/L	LDH U/L	ALP U/L	GGT U/L	Protein mg/L
MALE
24 h post exposure
0	0.16	196.8	37.6	5.9	92.7
0.05	0.21	168.6	38.8	6.7	84.2
0.25	0.36*	275.4	64.7	12.5**	115.4
5.0	1.05**	1306.2**	195.4**	19.5**	395.0**
90 days post exposure
0	0.26	225.7	76.4	5.6	115.4
0.05	0.27	174.8	78.2	6.3	79.8
0.25	0.42	237.2	108.5	9.5	102.3
5.0	1.18**	1353.2**	330.3**	16.1**	347.4**
FEMALE
24 h post exposure
0	0.17	163.6	34.9	5.1	78.8
0.05	0.18	163.0	28.8	6.6	91.2
0.25	0.30	312.7	63.4	12.5**	146.4
5.0	0.82**	1020.2**	144.1**	15.9**	292.6**
90 days post exposure
0	0.23	147.9	55.2	5.0	103.5
0.05	0.22	159.0	45.3	4.8	90.8
0.25	0.31	194.5	63.0	7.8	103.5
5.0	0.76**	566.2**	117.8**	15.8**	300.2**

ISSN: 1743-8977