Fig. 8From: Translocation of gold nanoparticles across the lung epithelial tissue barrier: Combining in vitro and in silico methods to substitute in vivo experimentsTEM images of intracellular particles in the A549 CML. (a) Agglomerates, (b, c) small agglomerates and (d) single particles in the cytoplasm and (e) particles next to the cell nucleus 24Â h after exposure to 100Â ng/cm2 18Â nm AuNP in the ALICE system. In (b) and (c) the surface of the monolayer (top left) and the PET membrane on which the CML were grown (bottom right) can be seen. The arrows are pointing towards the particles. (e: without lead citrate and uranyl acetate staining)Back to article page