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Table 3 Oxidative stress and inflammation biomarkers in subjects before and after 5-h exposure in a chamber with or without filtration of inlet air from a street

From: Controlled exposure to particulate matter from urban street air is associated with decreased vasodilation and heart rate variability in overweight and older adults

 

Particle filtered air

Non-filtered air

 

Before

After

Before

After

BH4 (mmol/L)

11.7 (7.7;16.8)

9.5 (5;17.3)

12.1(6.9;18.4)

10.6 (4.5;15.6)

BH2 + biopterin (mmol/L)

6.2 (4.2; 9)

4.9 (3.6;7.9)

6.5 (4.4;8.6)

4.6 (3.1;6.6)

Total biopterins (mmol/L)

18.1 (13.9;24)

14.6 (10.6;24.6)

19 (13.9;25)

15.5 (9.9;20.1)

BH2/BH4 (mmol/L)

0.52 (0.31;0.96)

0.46 (0.3;1.13)

0.53 (0.34;0.83)

0.44 (0.27;1.20)

Uric acid (mmol/L)

304 (152;421)

298 (157;440)

290 (163;449)

314 (171;431)

Ascorbic Acid (mmol/L)

56 (14;88)

57 (6;91)

56 (10;90)

61 (14;90)

Dehydroascorbic acid (mmol/L)

1.16 (0;5.0)

1.2 (0;4.4)

1 (0;5.0)

1.2 (0;5.5)

%Dehydroascorbic acid

2.4 (0;14.6)

2.5 (0;9.9)

2.1 (0;11.1)

1.7 (0;9.4)

C-reactive protein (mg/L)

1.1 (0.3;4.5)

1.1 (0.3;5.5)

1.1 (0.35;6.1)

1.1 (0.3;6.3)

Leukocytes (×109 cells/L)

5.2 (2.9;8)

5.85 (3.7;9.6)

5.2 (3.3;8)

6.2 (4.3;10.2)

Neutrophils (×109 cells/L)

2.7 (1.7;4.2)

3.25 (1.9;5.2)

2.9 (1.4;4.6)

3.5 (2.1;5.4)

Lymfocytes (×109 cells/L)

1.8 (0.7;3.1)

1.95 (0.9;3.5)

1.8 (0.9;3.1)

2.05 (0.9;3)

Monocytes (×109 cells/L)

0.2 (0.1;0.5)

0.3 (0.1;0.4)

0.2 (0.1;0.4)

0.3 (0.2,0.5)

Eosinophils (×109 cells/L)

0.2 (0.1;0.5)

0.1 (0.1;0.5)

0.2 (0.1;0.4)

0.2 (0.1;0.5)

  1. BH4 tetrahydrobiopterin; BH2 Dihydrobiopterin. Values are medians (5th;95th percentiles).