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Table 1 The result of acute toxicity of G5 PAMAM nanoparticles in mice

From: Cationic nanoparticles directly bind angiotensin-converting enzyme 2 and induce acute lung injury in mice

Group

Dose

Animal number

Number of animals

Mortality

Livability

(μg/g)

(n)

dead/dosed

p

q

I

0

6

0

0.00

1.00

II

7.35

6

1

0.17

0.83

III

10.5

6

2

0.33

0.67

IV

15

6

5

0.83

0.17

V

21.43

6

6

1.00

0.00

VI

30.61

6

6

1.00

0.00

  1. The percent mortality was recorded at 48 hrs after treatment with G5 PAMAM nanoparticles.
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Particle and Fibre Toxicology

ISSN: 1743-8977

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