Figure 2
From: Why does the hemolytic activity of silica predict its pro-inflammatory activity?
Cytotoxic activity of different silica particles in primary murine macrophages. LPS-primed primary murine macrophages were incubated with 20 cm2/ml of silica for 6 h and then evaluated for cell viability by means of the WST-1 assay. The silica samples included a commercial quartz (Qz-1), the same quartz heated at 800°C (Qz-2), a vitreous silica (VS), a pure quartz (Qz-3) and the pure quartz etched with HF (Qz-4). ATP (5 mM) was used as positive control. Results are expressed as percentage of the control (macrophages not exposed to silica particles -Ctl). Values are mean ± SD from at least three independent experiments. ***p < 0.001 vs control not exposed to silica particles.