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Table 3 Summary of histopathology findings

From: Short versus long silver nanowires: a comparison of in vivo pulmonary effects post instillation

Responses observed in lung tissues

S-AgNWs

L-AgNWs

Day 1

Day 7

Day 21

Day 1

Day 7

Day 21

Cellular Exudate in Alveoli

 

X

X

 

X

X

Epithelial Sloughing

  

X

X

X

 

Langhans Cells in Tissues

 

X

X

   

Tissue Granulomas

  

X

 

X

X

*Alveolar Inflammation

   

X

X

 

*Bronchiolar Inflammation

    

X

 

*Particle- Associated Inflammation

X

X

X

X

X

X

  1. “*” indicates that results were confirmed by statistical comparisons to control groups at a p value ≤ 0.05.