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Figure 3 | Particle and Fibre Toxicology

Figure 3

From: Nitric oxide and superoxide mediate diesel particle effects in cytokine-treated mice and murine lung epithelial cells — implications for susceptibility to traffic-related air pollution

Figure 3

ROS changes and cell injury in cytomix + DEP-treated cells. (A) ROS production, measured by fluorescence of H2DCFDA in saline- and cytomix-treated LA-4 cells exposed to DEP (25 μg/cm2 × 2 h). Data are expressed as mean fold increase (± SEM) over control cells and is representative of three independent experiments. Significance ( p < 0.05) indicated by: * vs. control; ** vs. DEP. (B) Cytotoxicity in saline- or cytomix-treated LA-4 cells with or without exposure to DEP (25 μg/cm2 × 24 h) based on LDH release. Data are expressed as mean fold-increase (± SEM) over saline-exposed cells and is representative of three independent experiments. Significantly ( p < 0.05) greater injury is indicated by: * vs. All other treatments.

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Particle and Fibre Toxicology

ISSN: 1743-8977

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