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Figure 6 | Particle and Fibre Toxicology

Figure 6

From: Use of back-scatter electron signals to visualise cell/nanowires interactions in vitro and in vivo; frustrated phagocytosis of long fibres in macrophages and compartmentalisation in mesothelial cells in vivo

Figure 6

Representative cytospin images of lavaged cells from the pleural space after 24 hour treatment with AgNWs. A) AgNW3 inside a pleural macrophage showing complete phagocytosis. B) Pleural macrophage with a fully phagocytosed AgNW5 (B) and AgNW10 (C). D) A pleural macrophage with increased cell size to phagocytose AgNW14. E) Frustrated phagocytosis after AgNW28 exposure. 3 macrophages sharing 2 long fibres. All images are shown at 100x magnification with a 10 μm scale bar.

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