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Figure 3 | Particle and Fibre Toxicology

Figure 3

From: Use of back-scatter electron signals to visualise cell/nanowires interactions in vitro and in vivo; frustrated phagocytosis of long fibres in macrophages and compartmentalisation in mesothelial cells in vivo

Figure 3

THP-1 membrane integrity and proliferation/metabolic activity. A) Measurement of membrane integrity plotted as % LDH release based and positive and negative control. Only AgNW28 lead to a significant release of LDH into the supernantant. B) Proliferation and metabolic activity was measured using alamarBlue®. Cell treated with AgNW28 showed decreased proliferation. Significance versus vehicle control *P <0.05, **P <0.01. Data represent mean ± s.e.m. of n = 5.

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