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Table 1 Subject demographics, pulmonary function data and breathing parameters (Mean ± SD)

From: Experimental determination of the respiratory tract deposition of diesel combustion particles in patients with chronic obstructive pulmonary disease

 

Healthy (n = 7)

COPD (n = 10)

  

% predicted

 

% predicted

Age (yrs)

30 ± 8

 

67 ± 7

 

Gender

2 M/5 F

 

7 M/3 F

 

Height (cm)

168 ± 9

 

171 ± 7

 

Weight (kg)

63 ± 5

 

73 ± 10*

 

Pack years

0

 

44 ± 19

 

FEV1 (L)

3.71 ± 0.96

107 ± 12

1.80 ± 0.45

66 ± 16

FEV1/FVC

0.79 ± 0.04

95 ± 4

0.49 ± 0.08

65 ± 10

FVC (L)

4.44 ± 1.09

110 ± 10

2.85 ± 0.63

81 ± 18

VC (L)

4.69 ± 1.21

115 ± 14

3.69 ± 0.77

102 ± 22*

TLC (L)

6.13 ± 1.31

109 ± 11

6.9 ± 0.9

112 ± 12

RV (L)

1.40 ± 0.20

 

3.24 ± 0.58

 

RV/TLC

0.24 ± 0.04

 

0.47 ± 0.08

 

PEF (L/s)

8.15 ± 1.66

105 ± 7

5.51 ± 1.70

75 ± 20

MEF50 (L/s)

4.02 ± 1.14

85 ± 21

0.78 ± 0.33

20 ± 8

MEF25 (L/s)

1.56 ± 0.54

 

0.17 ± 0.06

 

DLCO(SB)a

8.46 ± 1.99

92 ± 13

5.14 ±0.64

62 ± 12

DLCO/VA a

1.65 ± 0.06

92 ± 3

0.96 ± 0.19

70 ± 11

MV (L/min)

8.4 ± 1.5

 

10.6 ± 2.9

 

f (breaths/min)

10.7 ± 3.6

 

13.1 ± 3.4

 

VT (L)

0.86 ± 0.26

 

0.86 ± 0.28

 
  1. Abbreviations: MEF25/50 = maximum expiratory flow rate at 25% and 50% of VC respectively, DLCO(SB) = single-breath diffusion capacity for CO [mmol/min/kPa], DLCO/VA = diffusion capacity normalized to lung volume [mmol/min/kPa/L], MV = minute ventilation, f = breathing frequency, VT = tidal volume.
  2. *p < 0.05, p < 0.01, p < 0.001.
  3. a n = 5 for healthy subjects.