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Figure 3 | Particle and Fibre Toxicology

Figure 3

From: An in vitro liver model - assessing oxidative stress and genotoxicity following exposure of hepatocytes to a panel of engineered nanomaterials

Figure 3

Effect of 20 μg/cm2 of ENPRA nanomaterials on the oxidation of DCFH to DCF in C3A cells with and without Trolox pre-treatment. The cells were exposed to cell medium (control) or NMs for 6 or 24 hr. Results are exposed as mean fluorescence intensity minus corresponding control traces (±SEM) from three experiments (n = 3), significance indicated by * = p < 0.05 and ** = p < 0.005, when decrease in fluorescence is compared to cells not treated with Trolox (T) before exposure to the NMs.

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