Figure 6
From: Type I interferon and pattern recognition receptor signaling following particulate matter inhalation
Effects of GMA-SS inhalation exposure on pulmonary type I interferons and associated pattern recognition receptors. Relative mRNA levels of interferon alpha (Ifna – recognizes interferon alpha 1, 5 and 6), interferon beta (Ifnb – recognizes interferon beta 1), and the pattern recognition receptors Ddx58 (DEAD box polypeptide 58; RIG-I) and Ifih1 (interferon induced with helicase C domain; MDA5) were increased in the lung in reference to sham (dotted line). *p<0.05 vs sham.