Figure 4

Histological findings in lung tissue of exposed animals. A . The number of foci of particle-laden macrophages forming granulomas in the lungs. Animals infected with T. gondii alone were not included as no foci of particle-laden macrophages were observed. B . The number of foci of necrosis and inflammation unassociated with pigment and consistent with T. gondii infection. C. Difference in interstitial inflammation scores for the various groups. D . Pleuritis scores for each group. Data are represented as mean ± SEM. Statistical significance was determined with Kruskal-Wallis one-way ANOVA and Dunn’s post-test. * = p < 0.05, indicate significant differences from PBS controls and f  = p < 0.05, indicate significant differences from SWCNT.