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Figure 7 | Particle and Fibre Toxicology

Figure 7

From: Coating carbon nanotubes with a polystyrene-based polymer protects against pulmonary toxicity

Figure 7

Effects of MWCNT in vivo in mice - lung mRNA content. Panel a: HO-1, TNF-a, CXCL2, a-collagen-1, and a-collagen-3 mRNA expression in the lungs of mice 7 days after intratracheal instillation of vehicle or of 10 or 100 μg of NT1, NT2, or NT3. Results are expressed as the ratios over RPL13 mRNA levels and represented as box and whisker plots of values from 5-6 animals. Abbreviations are the same as in Figure 1. *: p < 0.05 vs. control condition. Panel b: HO-1, TNF-a, CXCL2, a-collagen-1, and a-collagen-3 mRNA expression in the lungs of mice 180 days after intratracheal instillation of vehicle or of 10 or 100 μg of NT1, NT2, or NT3. Results are expressed as the ratios over RPL13 mRNA levels and represented as box and whisker plots of values from 5-6 animals. Abbreviations are the same as in Figure 1.

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