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Figure 6 | Particle and Fibre Toxicology

Figure 6

From: Coating carbon nanotubes with a polystyrene-based polymer protects against pulmonary toxicity

Figure 6

Effects of MWCNT in vivo in mice - lung histology. Panel a: Lung histology 1 day after a single intratracheal instillation of vehicle or NT1, NT2 or NT3 (100 μg/mouse, magnification ×20). Abbreviations are the same as in Figure 1. Inserts are higher magnification views (×40) of the carbon nanotube agglomerates. Panel b: Lung histology 30 days after a single intratracheal instillation of vehicle, NT1, NT2, or NT3 (100 μg/mouse, magnification ×20). Abbreviations are the same as in Figure 1. Inserts are higher magnification views (×40) of carbon nanotube agglomerates. Panel c: Quantification of the number and size of carbon nanotube agglomerates in lungs of mice 24 hours, 1 month, or 6 months after a single intratracheal instillation of 100 μg NT1, NT2, or NT3. Results are represented as box and whisker plots of values from 5 animals (five fields per animal). *: p < 0.05 between groups.

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