From: Effects of copper nanoparticle exposure on host defense in a murine pulmonary infection model
Animal Group | Total number of cells/mouse (× 10 3 ± SE) | Total protein (μg/mL ± SE) | LDH Activity (U/L ± SE) |
---|---|---|---|
Inhalation study | |||
Sham exposure | 105 ± 14 | 127 ± 4 | 100 ± 6 |
Cu NP | 1,210 ± 106*** | 544 ± 38*** | 336 ± 29*** |
Instillation study | |||
Sham exposure | 149 ± 32 | 107 ± 7 | 163 ± 17 |
Cu NP Low, 3 μg/mouse | 186 ± 70 | 122 ± 17 | 193 ± 21 |
Cu NP Medium, 35 μg/mouse | 977 ± 156** | 160 ± 13* | 236 ± 21* |
Cu NP High, 100 μg/mouse | 882 ± 121** | 219 ± 37* | 341 ± 39** |
† p by one-way ANOVA | p < 0.001 | p < 0.01 | p < 0.001 |