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Figure 4 | Particle and Fibre Toxicology

Figure 4

From: Effects of copper nanoparticle exposure on host defense in a murine pulmonary infection model

Figure 4

Representative micrographs and quantitative histopathologic evaluations of lung tissues from animals exposed to Cu nanoparticles (NPs). Micrographs of lung sections stained with H&E from mice exposed to Cu NPs by sub-acute inhalation (A) or intratracheally instilled with a low (3 μg, B), medium (35 μg, C), or high (100 μg, D) dose or sham-exposed (E). Histopathologic evaluation was performed by light microscopy in four categories (inflammation, cell injury, fibrosis, and congestion) each employing a five point scale (F). Data are expressed as mean ± SE; *p < 0.05, **p < 0.01, ***p < 0.001 significantly different from sham-exposed mice.

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