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Figure 9 | Particle and Fibre Toxicology

Figure 9

From: Progressive severe lung injury by zinc oxide nanoparticles; the role of Zn2+ dissolution inside lysosomes

Figure 9

Transmission electron microscopy images of lungs at 4 wks after instillation of ZnONP at 150 cm2 /rat. (A), vehicle control; (B - D), ZnONP treatment group. Bar scale: B and C = 2 μm; A and D = 5 μm. Collagen bundles (arrowhead) were found in the perivascular region (B) and alveolar interstitium (C) where they co-localized with eosinophils (black arrow) and PMN. Foamy macrophages (white arrow) were localized in the alveolar spaces.

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