Figure 14From: Progressive severe lung injury by zinc oxide nanoparticles; the role of Zn2+ dissolution inside lysosomes Diagram of lung injury caused by ZnONP instillation. ZnONP induced (1) goblet cell hyperplasia, (2) thickening of bronchiolar smooth muscle layer, (3) eosinophilia, (4) fibrosis with increased numbers of myofibroblasts (yellow) and collagen (thin blue fibres), (5) perivascular edema, and (6) type II cell hyperplasia.Back to article page