Figure 4
From: Particulate matter air pollution causes oxidant-mediated increase in gut permeability in mice
Exposure to particulate matter causes nitration and oxidation of tubulin and disruption of tight junctions in intestinal cell monolayers. The effect of PM on tubulin (A) nitration (nitrotyrosination) and (B) oxidation (carbonylation) in Caco-2 cell monolayers are shown. H2O2 (0.5 mM) was used as a positive control. (C) Images from high-resolution laser scanning confocal microscopic evaluation of intestinal cell monolayers stained for F-actin are shown.