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Table 1 Amounts of dopamine and its metabolites (pg mg-1 protein) in each part of the brain.

From: In utero exposure to a low concentration of diesel exhaust affects spontaneous locomotor activity and monoaminergic system in male mice

Brain region

Group

Content (pg mg-1 protein)

  

Dopamine

DOPAC

3-MT

HVA

Striatum

Control

270999 ± 30968

20710 ± 2573

21841 ± 3409

32479 ± 3492

 

Exposed

319714 ± 14364

20197 ± 685

22587 ± 1386

31276 ± 1956

Hippocampus

Control

1520 ± 350

N.D.

714 ± 143

23816 ± 8826

 

Exposed

951 ± 101

N.D.

449 ± 35

4419 ± 392**

Midbrain

Control

4387 ± 486

2491 ± 191

773 ± 71

3864 ± 225

 

Exposed

3446 ± 361

1798 ± 110*

555 ± 40*

2847 ± 238*

Cerebellum

Control

202 ± 29

N.D.

N.D.

3225 ± 1152

 

Exposed

197 ± 46

N.D.

N.D.

4367 ± 1343

Brainstem

Control

17959 ± 646

57513 ± 2294

N.D.

2952 ± 252

 

Exposed

15775 ± 395*

51445 ± 2244

N.D.

5382 ± 517**

  1. Data are presented as mean ± SEM (n = 10 per group). The statistical significance is shown as *P < 0.05, **P < 0.01; ND, not detectable. Abbreviations: DOPAC, 3,4-dihydroxyphenylacetic acid; HVA, homovanillic acid; 3-MT, 3-methoxytyramine.