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Figure 6 | Particle and Fibre Toxicology

Figure 6

From: Ultrafine particles from diesel vehicle emissions at different driving cycles induce differential vascular pro-inflammatory responses: Implication of chemical components and NF-κB signaling

Figure 6

UFP2 but not UFP1 activated the NF-κB signal transduction pathway. HAEC grown to confluence were infected with Adv-LacZ and Adv-NF-κB-Luc overnight. The cells were then treated with 50 μg/ml (6.25 μg/cm2) of UFP1 or UFP2 for 24 hours. Cells were lysed and luciferase activities and β-Galactosidase activities were measured as described in methods. NF-κB reporter activities were normalized to LacZ levels and expressed as relative to control (C = control; * versus control, n = 3, P < 0.05; ** versus control, n = 3, P < 0.01)

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Particle and Fibre Toxicology

ISSN: 1743-8977

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