Skip to main content

Table 2 Experimental findings of neurobiological effects of specific ENPs

From: Risks from accidental exposures to engineered nanoparticles and neurological health effects: A critical review

End-point

In vivo

In vitro

References

Cell morphology changes

Al2O3, TiO2

Fe2O3, QDs

[11, 61, 67, 69, 70]

Increased inflammation signs and markers

MnO2

 

[56, 62]

Increased oxidative stress

TiO2, QDs

Degussa P25, ferritin, C60, Ag

[61, 67, 69, 72]

Antioxidative effects (inconsistent effects)

 

CeO, YO, C60

[73–76]

Neuron function (inhibition and facilitation)

MnO2, Zn, TiO2, QDs

Mn, Ag, ZnO, CuO, CNTs, TiO2, QDs

[61, 67, 68, 77, 88]

Behaviour (negative effect)

MnO2

 

[62]

Development and differentiation (inconsistent effects)

TiO2

Fe2O3, Ag, TiO2

[65, 66, 84]

Accelerated protein fibrillation

 

TiO2, CNT, QDs, CeO, copolymer particles

[86, 87]